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The 9 Best CBD Oils for Addiction in 2022

The first thing we want to say is that if you are struggling with addiction, you are not alone. In 2010, it was reported that one in ten Americans over the age of 12 deal with addiction as well, that’s almost 24 million people. Sadly, those rates have only continued to go up since then. This is a serious problem that many people are fighting right now.

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Some of the statistics surrounding addiction are staggering. Addiction costs this country billions of dollars because of crime, healthcare, and so on. Casual alcoholism is on the rise among young people and more than 95% of people who receive treatment for alcohol don’t believe that they need it. No matter how you look at it, the truth remains that millions of Americans are struggling with harmful substances and they’re doing it on their own.

Table of Contents

  • America’s Approach
  • CBD for Addiction
  • The 9 Best CBD Oils for Addiction
    • 1. Cannabidiol Life
    • 2. Pure Hemp Botanicals
    • 3. CBD Life
    • 4. Endoca
    • 5. Charlotte’s Web
    • 6. Kat’s Naturals
    • 7. Bluebird Botanicals
    • 8. 4 Corners Cannabis
    • 9. Elixinol

    America’s Approach

    “The Opioid Crisis” are words that everyone is familiar with, and that is the big focus in the country at the moment. Most states are advocating against obtaining opioid medications for pain at all, citing the fact that it only takes three days to become dependent. However, there are a plethora of other substances that people get addicted to. Many of them are drugs used to treat addiction in the first place.

    Abstinence-only approaches to addiction have been proven to be ineffective. American Addiction Centers reported that Alcoholics Anonymous, an abstinence program for alcoholics, only works in roughly 8-12% of participants. In fact, harm reduction initiatives such as needle exchange programs have been shown to produce better results across the board. Policy in America is a long way away from allowing this to become a reality nationwide; most places take those who are addicted to dangerous drugs and provide them with safer alternatives to their drug of choice in an effort to curb addiction but that doesn’t work either. Dependence on Suboxone or Methadone is not ideal for many people.

    CBD for Addiction

    When posed the question “how can you protect yourself against addiction?” most people have the same answer: avoid pharmaceuticals. That’s because many of the drugs people are addicted to are pharmaceuticals, and of course, plenty of them have side effects like anxiety and depression, which are contributing factors to addiction. It’s a seemingly endless cycle.

    A new question to ask is “how can CBD help addiction?” More and more people are turning to plant medicine. Plant medicine was used for thousands of years before traditional medication and they will likely exist until the end of time. Many plants interact with our bodies, particularly our nervous system, and take natural actions in our body to help ease our ailments and improve our health.

    Another great thing about plant medicine is that it rarely has side effects. CBD is one of the plant medicines that has no side effects and can help alleviate many of the symptoms that lead to addiction or are associated with coming down from drugs. While the symptoms and causes for addiction are going to vary from person to person, some of the most common problems associated with addiction that CBD helps with include:

    If you’d like to find out what CBD products might work for you, check out the following.

    The 9 Best CBD Oils for Addiction

    1. Cannabidiol Life

    Cannabidiol Life makes it their practice to provide only the highest quality products through the best extraction method according to their evidence from third-party testing. According to CBD Life, their top picks for extraction are cradling and Supercritical CO2. Both ensure the extraction of “full spectrum” CBD rather than just pulling out one compound on its own. Generally, CBD oil taken as a tincture is an overall effective treatment for addiction as CBD tinctures slowly build in the system. This leads to a longer lasting and slow incremental change. Because of that, we recommend Cannabidiol Life’s CBD Oil. This particular oil comes in 750 mg, 1,500 mg, and 3,000 mg strengths. CBD Life states that their 3,000 mg tincture is that highest dosage in that kind of product available on the web today.

    Depression and anxiety are often comorbid with addiction and if this is something you’re currently facing, you may want to start with a stronger dose of CBD oil. Cannabidiol activates the 5-HT1A serotonin receptor to help with anxiety, addiction, appetite, sleep, and can even relieve withdrawal symptoms like nausea and vomiting. With that said, everyone is going to have different needs when it comes to CBD dose. You should start at a low dose and work your way up. If you are looking to taper off of a powerful chemically enhanced opiate, a stronger dose of CBD may be where you should start because your body is used to a stronger chemical response to the pain you’re feeling.

    If you are that individual who started with pharmaceutical pain pills like oxycodone due to physical pain, we agree that you should seek out a safer alternative. If oral CBD products aren’t what you’re interested in, we would recommend treating the pain acutely with Soothe Balm. In addition to the highly therapeutic benefits of CBD, this formula includes other naturally calming botanicals including arnica, lavender, St. John wort, calendula, and comfrey root. The combined efforts of these powerful plants make for potent and acute relief from physical pain without side effects and a lifetime of addiction.

    • Product Types: Tincture, Vape Liquid, Capsules, Edibles, Isolates, Crystals, Wax, Water
    • Our Recommended Product for Addiction: CBD OIL 3,000 mg for relief of the anxiety, depression, and nausea that may accompany addiction and CBD Soothe Balm for acute relief from physical pain.

    2. Pure Hemp Botanicals

    Pure Hemp Botanicals is passionate about the purity of their products. CBD is a booming industry but, as it is, it is not very regulated. Pure Hemp Botanicals came up with their own answer to that problem and seeks to allay customer concerns in their own way. Consumers have access to a first-hand experience with a video tour of the facilities and of course, published lab tests results for each batch. Customers can follow the process from soil to oil.

    Their non-GMO source hemp is organically cultivated in Colorado, and subjected to a gentle, full-spectrum extraction process before being compounded into potent and high-quality teas, capsules, vape liquids, and tinctures. They offer a wide range of products to help individuals with a myriad of addictions. For instance, those who are looking to quit smoking and remain smoke-free may benefit from vaping their product. The tea contains other natural botanicals that are known to relieve acute anxiety and help with calming the mind and body including hibiscus, chamomile, and lavender which is said to help with racing thoughts, and chronic anxiety.

    The company also offers a full spectrum tincture for long-lasting relief from anxiety and depression as well as continual regulation of sleep to combat insomnia that often accompanies the intake of harmful drugs like amphetamines.

    • Product Types: Tincture, Softgels, Capsules, Mints, Crystals, Vape Liquid, Tea
    • Our Recommended Product for Addiction: CBD Vape, for general calm; for relief from insomnia the hibiscus tea; and for long-lasting relief from anxiety and depression try the CBD Tincture.

    3. CBD Life

    CBD Drip wants to be known not only for its transparency but also for its quality and accessibility. Their source hemp is pesticide-free, European-grown, Non-GMO, CO2 Extracted, and full-spectrum. If you suffer with addiction accompanied by anxiety one of the best methods to help treat this problem is through a CBD oil like this one, guaranteed pure full-spectrum plant medicine.

    From their EcoDrops line we recommend Dream. This “custom-crafted” blend includes the relaxing and defrazzling botanicals lavender, valerian, and roman chamomile. This is a great blend for treating insomnia, but can be used for general calming as well. Another option is the company’s unflavored CBD oil, which can be vaped, and comes in strengths of 14.5 mg, 58 mg, 140 mg, 500 mg, and 750 mg.

    Vaping is another great option for individuals looking for quick relief from intense craving. This can be used regularly to help when tapering off of any drug. Naturally, this is an effective use for individuals who are looking to stop smoking. If you don’t want to taste your CBD, CBD Drip’s CBD capsules are another good choice. They are both vegan and gluten-free. Each potent capsule each contains 30 mg of multi-cannabinoid, full-spectrum hemp extract.

    • Product Types: Oral Drops, Capsules, Vape Liquid
    • Our Recommended Product for Addiction: CBD Oil and Vape Liquid, Dream EcoDrops, and capsules. You’ll have to adjust the dose according to your needs.

    4. Endoca

    For Endoca, CBD is more than a product, it’s a calling. This family-run CBD company grows and harvests their own organic hemp on a sustainable permaculture farm, using self-built equipment. The company is even developing a self-sufficient village to support its eco-friendly processing and manufacturing plant. The company runs a charitable foundation to supply CBD to individuals and families in need, operates a seed bank, a meditation and collaborative wellness center, and more. This is a company passionate about wellness, of people and the planet we live on.

    Endoca CBD products match their ethics bringing only the highest quality products, closely overseen from soil to oil. The hemp used to make their products is organically grown in Denmark, an area known for low pollution. Third-party lab testing is just another practice that makes Endoca shine where consumers may view results through the Endoca website. Of their many products, the best CBD for addiction is Endoca’s CBD oil oral drops. Each of these products is cold-extracted, containing terpenes, vitamins, ketones, amino acids, and co-nutrients, and is available in strengths of 300 mg, and 1500 mg.

    • Product Types: Tincture, Drops, Capsules, Suppositories, Ovules, Crystals, Salves, Body Butter, Chewing Gum
    • Our Recommended Product for Addiction: CBD Oil drops with dosage based on user’s level of CBD oil experience.

    5. Charlotte’s Web

    Charlotte’s Web gets its name from Charlotte, a young girl who made a dramatic recovery from a rare and debilitating seizure disorder. Charlotte so inspired the Stanley Brothers that they started this line of CBD products. Charlotte’s Web’s line of commercial CBD tinctures, capsules, and topicals use the same proprietary strain of source hemp but are uniquely formulated to address common issues like inflammation, fatigue, and anxiety.

    All are made from hemp grown organically and sustainable in Colorado and subjected to broad-spectrum extraction, which preserves the full entourage of beneficial plant compounds. Their CBD tincture is an excellent choice for those who suffer from addiction as well as for individuals who are looking to come down from and abstain from addictive substances. The formula comes in mint and chocolate flavors and helps the body maintain a sense of calm, regulate sleep, and regulates the central nervous system.

    Today it is common practice to prescribe harmful and dangerous pharmaceuticals for pain relief. CW has a powerful alternative. Topical creams are great for acute instances of pain or inflammation. In addition to CBD, the cream contains many natural botanicals to aid with relief from pain such as arnica oil, a homeopathic pain reliever. Additionally, the cinnamon found in the cream helps warm and relax the muscles.

    • Product Types: Capsule, Tincture, Balm, Cream
    • Our Recommended Product for Addiction: CBD Oil or for those suffering from physical pain and inflammation, CBD topicals. Remember to adjust the dose according to your needs.

    6. Kat’s Naturals

    Kat’s Naturals offers a full spectrum premium CBD Hemp Oil. Their flagship product is “Heal” and it is definitely one of the best CBD oil products readily available in the US. The company sources their hemp from Northern Europe, a region known for low pollution and optimal growing conditions.

    The industrial hemp is then subjected to a rigorous CO2 extraction method and compounded into a 99% pure CBD isolate. Each bottle is full of cannabinoids like CBD that help to regulate the immune system, heal the nervous system, and contains good fats like Omega-3 and Omega-6 help to slow down aging and promote healthy digestion. For those suffering from anxiety and insomnia related to either come down or cravings, you could try Relax.

    Relax combines a full spectrum CBD with sweet orange oil and hops. Hops are a bitter sedative that is particularly helpful for insomnia that accompanies exhaustion due to emotional physical or mental pain. Hops may also ease the symptoms of too much stimulation, giving you a chance to truly… well, relax. Both Heal and Relax offer a dopamine boost to help regulate motor control, improve cognition and send positive “rewards” messages to the brain. Dopamine is burnt out in the brain from drug use, particularly stimulants.

    If you used to smoke or are trying to quit smoking, definitely try Kat’s vape liquid. Vaping means for rapid release and will help you curb cravings as fast as they come on. Before swallowing heavy and harmful pharmaceuticals for physical pain, you could also give Kat’s Deep Pain Cream a try. Apply directly to the affected area for acute pain relief.

    • Product Types: Tinctures, Vape Liquid, Topicals, Edibles
    • Our Recommended Product for Anxiety: Heal and Relax CBD Oil blend or deep pain cream with dosage based on user’s level of CBD oil experience.

    7. Bluebird Botanicals

    Bluebird Botanicals is a principled company that supports organic and sustainable farming. The company has been granted a CGMP designation, offers true support to its employees, and even donates to autism research, homeless outreach, and more. The company also offers discounts to the disabled, veterans, and individuals with low income. They clearly believe in the power their products have to heal, which is something we support wholeheartedly. We also want to mention another accolade the company received. In 2016, Blue Botanicals was named #1 Hemp CBD Company as the 2016 Cannabist Awards.

    Bluebird’s oral CBD extracts are a premium long-lasting CBD products for anxiety, with three formulations offered in strengths of 250 mg or 1,000 mg. The “Signature” blend contains the most therapeutic ingredients. This CBD concentrate features hemp extract in hemp oil (containing raw and heated cannabinoids plus steam-distilled hemp terpenes) with added wildcrafted frankincense extract, a botanical known to help induce calm, heal the signs of aging, and reduce general stress as well as negative emotions. We like the Signature Blend for individuals coping with stress related to drug cessation, and for individuals who are looking to curb cravings.

    For the fastest relief from anxiety, Bluebird’s CBD 333 mg vape liquid is the preferred choice. Vaping offers the fastest delivery to the bloodstream so it will act fast; however, the effects may not be as long. Additionally, this product is the perfect fit for individuals who are looking to quit or have recently quit drugs inhaled through the lungs, like nicotine. The action of vaping may help stave off those cravings for a cigarette.

    We also love that Bluebird Botanicals publishes third-party lab results for every single batch of CBD that passes through their hands.

    • Product Types: Tincture, Capsule, Vape Oil, Isolates
    • Our Recommended Product for Addiction: CBD Oil extracts, or vape liquid, with your dosage based on your level of CBD oil experience.

    8. 4 Corners Cannabis

    With over 20,000 hours of CBD research between them, the founders of 4 Corners Cannabis have unparalleled expertise and they have come up with an incredible product. As growers, the company has total control of their products and have worked painstakingly hard to provide you with a full spectrum CBD oil that has what is known as the entourage effect. This is the union of the multiple compounds of a cannabinoid oil.

    With this principle in mind, the company works with a CBD-concentrated “super strain” of non-industrial hemp dubbed “Ma’at,” and focuses on a broad-spectrum extraction method that employs gentle “cradling” in organic, food-grade ethanol. Cradling is the most painstaking extraction process with the highest concentration of purity available on the market. To ensure transparency, 4 Corners makes their third-party lab test results for each CBD oil batch public on their website.

    Long-term use of drugs can affect the mind and body. Fortunately, 4 Corners makes products to help heal both. For individuals who have experience motor impairment sensory processing issues or anxiety and depression from addiction and long term drug use, we recommend 4 Corners Cannabis oil available in strengths of 250 mg, 500 mg, and 1,000 mg. Be sure to adjust your dose according to your experience with the product and personal needs. As this product must be absorbed through the liver to get through the bloodstream, the product should be taken daily and you will see increased benefits when taken over time. If you are seeking fast relief, vape! Vaping goes straight into the bloodstream through your lungs, which can provide relief in as little as five minutes.

    • Product Types: Vape Liquid, Oral Tincture, Salve
    • Our Recommended Product for Addiction: CBD Oral Tincture and vape liquid with your dose based on your personal needs.

    9. Elixinol

    The founder of Elixinol got his start in 1991 when he launched 9bar, which was a healthy snack bar packed with heart-healthy hemp. Elixinol now sells an array of CBD products, including tinctures, capsules, liposomes, vape liquids, and topical balms. The company prides itself on the fact that all of these products contain the purest CBD possible. Elixinol is always working on expanding and even employs a team of medical professionals to research and develop their product formulations.

    The company sources its hemp from farms in Europe, Australia, and America. Once harvest, the company uses a chemical- and heat-free, broad-spectrum CO2 extraction process. This extraction preserves the benefits of CBD better than any other. The company’s standards of testing are impressive also, as they conduct tests both in house and third-party. These tests cover not only potency, but also microbiological contamination, heavy metals, pesticides, and terpene profile. The European-based labs employ equipment and personnel from the pharmaceutical industry, and all test results are posted online alongside product listings to promote customer awareness and trust.

    We like their vape and tinctures to help treat symptoms related to addiction. Their CBD products help to promote better sleep, reduced levels of anxiety, immune support, and offer a boost of dopamine. Their Natural Drops reach a strength of 3600 mg! That’s the highest we have seen on the market. If you are looking to quit smoking or have recently quit and need to curb cravings, vaping with CBD gives you the sensation of a cigarette without the harmful chemicals and nicotine all while inducing a sense of calm and bringing balancing relief to the nervous system.

    • Product Types: Tincture, Capsules, Liposomes, Spray, Balm

    Our Recommended Product for Addiction: CBD Natural Drops, oral delivery “X-Pen”, with dosage based on user’s needs or symptoms.

    Cannabidiol Oil for Decreasing Addictive Use of Marijuana: A Case Report

    This case study illustrates the use of cannabidiol (CBD) oil to decrease the addictive use of marijuana and provide anxiolytic and sleep benefits. Addiction to marijuana is a chronic, relapsing disorder, which is becoming a prevalent condition in the United States. The most abundant compound in the marijuana, which is called tetrahydrocannabinol (THC), has been widely studied and known for its psychoactive properties. The second most abundant component—CBD—has been suggested to have the medicinal effects of decreasing anxiety, improving sleep, and other neuro-protective effects. The mechanism of action for CBD has been suggested to be antagonistic to the psychoactive properties of THC in many locations within the central nervous system. Such action raises the issue of whether it might be beneficial to use CBD in isolation to facilitate withdrawal of marijuana use. The specific use of CBD for marijuana reduction has not been widely studied.

    The patient was a 27-y-old male who presented with a long-standing diagnosis of bipolar disorder and a daily addiction to marijuana use. In the described intervention, the only change made to the patient’s treatment was the addition of CBD oil with the dosage gradually decreasing from 24 to 18 mg. With use of the CBD oil, the patient reported being less anxious, as well as settling into a regular pattern of sleep. He also indicated that he had not used any marijuana since starting the CBD oil. With the decrease in the dosage to 18 mg, the patient was able to maintain his nonuse of marijuana.

    Cannabidiol (CBD) oil is a naturally occurring constituent of industrial hemp and marijuana collectively called cannabis. CBD oil is one of at least 85 cannabinoid compounds found in cannabis and is popular for its medicinal benefits. After tetrahydrocannabinol (THC), which is the most abundant compound in cannabis, CBD is the second most abundant. Other names for CBD oil include CBD-rich hemp oil, hemp-derived CBD oil, or CBD-rich cannabis oil. CBD is generally considered to be safe and has been used medicinally for decades. The suggested medicinal effects of CBD include decreasing anxiety, improving sleep, and providing other neuroprotective effects.

    THC is a cannabinoid and is the component that induces the euphoric psychoactive effect. Various cannabis plants can have different amounts of CBD and THC depending on the strain, and, thus, can provide different recreational or medicinal effects. The cannabinoid profile of industrial hemp or medical marijuana is ideal for people looking for the medical benefits of CBD without the high of the THC. The mechanism of action for CDB has been suggested to be antagonistic to the psychoactive properties of THC in many locations within the central nervous system, thus helping to attenuate the psychoactive behaviors of THC.1,2

    The mechanism of action of CBD is multifold.3,4,5 Two cannabinoid receptors are known to exist in the human body: CB1 and CB2 receptors. The CB1 receptors are located mainly in the brain and modulate neurotransmitter release in a manner that (1) prevents excessive neuronal activity, thus calming and decreasing anxiety; (2) reduces pain; (3) decreases inflammation; (4) regulates movement and posture control; and (5) controls sensory perception, memory, and cognitive function.4

    Anandamide, an endogenous ligand that occurs naturally within our bodies, binds to the CB1 receptors through the G-protein coupling system. CBD has an indirect effect on the CB1 receptors by stopping the enzymatic breakdown of anandamide, allowing it to stay in the system longer and to provide its medical benefits.6 CBD has a mild effect on the CB2 receptors, which are located in the periphery of the lymphoid tissue. The CBD helps to mediate the release of cytokines from the immune cells in a manner that helps to reduce inflammation and pain.4

    Other mechanisms of action of CBD include stimulation of vanilloid pain receptors, such as the transient receptor potential cation channel subfamily V member 1 (TRPV-1) receptor, which are known to mediate pain perception, inflammation, and body temperature.7 CBD may also exert its antianxiety effects by activating adenosine receptors that play a significant role in cardiovascular function, causing a broad anti-inflammatory effect throughout the body.7 At high concentrations, CBD directly activates the 5-HT1A serotonin receptor, thereby conferring an antidepressant effect.8 CBD has been found to be an antagonist at a potentially new third cannabinoid receptor (ie, G protein-coupled receptor 55, or GPR55), which resides in the caudate nucleus and putamen and can contribute to osteoporosis when stimulated.9

    Since the 1940s, a considerable number of published articles have addressed the chemistry, biochemistry, pharmacology, and clinical effects of CBD.10 The last decade has shown a notable increase in the scientific literature on CBD, owing to its identification as being beneficial in reducing nausea and vomiting, combating psychotic disorders, decreasing inflammation, lessening anxiety, reducing depression, improving sleep, and increasing a sense of well-being.11,12,13,14 Findings presented at the 2015 International Cannabinoid Research Society at their 25th Annual Symposium in Nova Scotia, Canada, reported that use of CBD was beneficial for treatment of liver fibrosis and inflammation, metabolic syndrome, overweight and obesity, anorexia/cachexia syndrome, and osteoarthritic and other musculoskeletal conditions.15

    Although studies have demonstrated the calming, anti-inflammatory, and relaxing effects of CBD, clinical data demonstrating the use of CBD to obtain help in marijuana withdrawal is minimal. One prior case study by Crippa et al16 documented the positive effects of using CBD for the treatment of marijuana withdrawal. The current case study offers further evidence that CBD is effective as a safe method of transitioning off marijuana without unwanted side effects.

    Presenting Concerns

    The patient was a 27-year-old male who presented with a long-standing diagnosis of bipolar disorder and a daily addiction to marijuana. His presenting concerns included erratic behaviors, anxiety, inconsistent sleep patterns, and irritability. He currently lives with his parents, works as a self-employed driver, and teaches chess to children. Informed consent was received from the patient.

    Clinical Findings

    The patient’s history included hospitalizations as a teenager for bipolar episodes. He came to the author’s clinic, Wholeness Center in Fort Collins, Colorado, in 2011 and was evaluated by a psychiatrist and naturopathic physician.

    The patient’s treatments for his bipolar disorder included pharmacological medications ( Table 1 ). Evaluations included (1) a basic, complete blood count; (2) a nutritional evaluation; (3) a comprehensive metabolic panel; (4) a lipid panel; (5) a measurement of methylene tetrahydrofolate reductase (MTHFR); (6) a celiac panel; (7) a measurement of thyroid function; (8) a measurement of iron levels; and (9) a quantitative electroencephalogram (qEEG).

    Table 1

    Patient’s Timeline, 2011–2015

    Date Presentation Medications Supplements Cannabidiol Oil
    06/20/2011 Initial psychological evaluation; diagnosis of bipolar disorder and depression, with difficulty processing information; buzzing in head and some disorientation; 2 manic periods in previous 10 mo, exacerbated by substance abuse; history of hospitalizations; micromanagement of life by mother. Regular marijuana use
    11/2011–06/2012 49 neurofeedback sessions. Marijuana use
    08/2012–10/2012 9 bodywork sessions. Marijuana use
    10/22/2013 No periods of mania/depression; 2 jobs. Marijuana use
    02/21/2014 Erratic moods with resumption of THC; stressed family with patient’s deterioration when using THC. Citalopram: 20 mg Marijuana use daily
    03/27/2014 Mood withdrawn and erratic; passiveaggressive behaviors. Citalopram: 20 mg
    Lamotrigine: 150 mg
    Marijuana use: 1–2 joints /night + pot brownies; admitted addiction to THC
    DEN: 3 caps TID
    Niacin: 2 caps BID
    O-3: 1 cap/d
    CoQ10: 150 mg/d
    Inositol: 2 scoops am & pm
    Probiotic: 1 cap/d
    Meriva: 1 cap/d
    05/08/2014 Contemplation of quitting THC; realization of connection with mood changes; concern of family about mood changes; limited social contact; works with Legos. Citalopram: 20 mg
    Lamotrigine: 150 mg
    Regular marijuana use
    DEN: 3 caps TID
    Niacin: 2 caps BID
    O-3: 1 cap/d
    CoQ10: 150 mg/d
    Probiotic: 1 cap/d
    07/10/2014 Less labile; mildly tired; no psychosis; continued marijuana use; less tension at home, with father home more often. Citalopram: 20 mg
    Lamotrigine: 150 mg
    Deplin: 15 mg
    Marijuana use 1 ×/wk
    DEN: 3 caps TID
    Niacin: 2 caps BID
    O-3: 1 cap/d
    CoQ10: 150 mg/d
    04/24/2015 Continuous destabilization; no evidence of psychosis; difficulty with abuse of marijuana; jobs teaching chess to kids and catering. Citalopram: 20 mg
    Lamotrigine: 150 mg
    Deplin: 15 mg
    Marijuana use daily
    DEN: 3 caps TID
    Niacin: 2 caps BID
    O-3: 1 cap/d
    CoQ10: 150 mg/d
    05/04/2015 Anxious, erratic moods; sensitive to gluten but no restriction; consumption of a lot of junk food; jobs teaching kids chess, making deliveries. Citalopram: 20 mg
    Lamotrigine: 150 mg
    Deplin: 15 mg
    No marijuana
    No supplements
    6 sprays PRN during day; 2 sprays QHS
    06/04/2015 Overall improved quality of sleep; slightly less anxious. Citalopram: 20 mg
    Lamotrigine: 150 mg
    Deplin: 15 mg
    No marijuana
    No supplements
    3–4 sprays PRN during day; 6 sprays QHS
    07/02/2015 Overall doing well; better sleep; anxiety under control; new job as Uber driver. Citalopram: 20 mg
    Lamotrigine: 150 mg
    Deplin: 15 mg
    No marijuana
    No supplements
    2 sprays PRN during day; 4 sprays QHS
    08/03/2015 Overall good sleep and no anxiety. Citalopram: 20 mg
    Lamotrigine: 150 mg
    Deplin: 15 mg
    No marijuana
    No supplements
    0 sprays PRN during day; 6 sprays QHS

    Abbreviations: THC, tetrahydrocannabinol; DEN, daily essential nutrients; cap(s), capsule(s); TID, 3 ×/d; BID, 2 ×/d; THC, tetrahydrocannabinol; PRN, when necessary; QHS, every bedtime.

    Dietary recommendations were then implemented as was a regimen of nutritional supplements. The patient also received neurofeedback sessions and bodywork. Prior to the period of the case study, he had been stable for a number of years.

    In time, the patient’s marijuana habit progressed to addiction. In May 2015, it was recommended that he begin taking CBD as a way of transitioning off the daily marijuana use and stabilizing his erratic moods.

    Diagnostic Focus and Assessment

    Clinical observations of the patient’s erratic behaviors, mood swings, and disorientation, together with the patient’s self-report of daily marijuana use, reinforced the diagnoses of bipolar disorder and addiction. He was administered the Pittsburgh Sleep Quality Index (PSQI)17 and the Hamilton Anxiety Rating Scale (HAM-A)18 prior to initiation of the CBD oil.

    Theraputic Focus, Assessment, and Follow-up

    The only addition that the author made to the patient’s treatment regime was the CBD oil. At the same time, the patient’s other supplement therapy was discontinued to simplify treatment, as no clear benefit was demonstrated. The initial regimen was 24 mg of the CBD oil, with 6 sprays PRN during the day and 2 sprays QHS. The dosage was gradually decreased from 24 to 18 mg, with the patient using no sprays during the day and 6 sprays at bedtime. The patient was seen for monthly appointments, including readministration of the PSQI and the HAM-A to evaluate the effectiveness and proper dosing of the CBD oil. CannaVest Company (Las Vegas. NV, USA), which had no involvement in the case study or distribution of the product, provided the CBD oil that was administered to the patient.

    Outcome Measures

    Pittsburgh Sleep Quality Index

    The PSQI is a standardized and validated self-report instrument that measures sleep quality over the prior month. Low scores indicate better sleep. A score under 5 means that you have no sleep concerns. 5 to 10 is fair quality sleep.

    Hamilton Anxiety Rating Scale

    The HAM-A scale is a standardized and validated measure of anxiety in an adult population that has been in active use for decades. A score of 17 or less indicates mild anxiety in terms of severity. A score from 18 to 24 demonstrates mild to moderate anxiety severity. Last, a score of 25 to 30 indicates moderate to severe anxiety.

    Results

    Using the CBD oil, the patient was able to maintain nonuse of marijuana. With a subsequent, gradual decrease in anxiety, the patient was able to maintain a regular sleeping schedule ( Table 2 ). He was able to get a more secure job as a self-employed driver, and he continued to teach chess to children. He also became more interactive with his family and friends.

    Table 2

    Date PSQI HAM-A
    05/4/2015 7 16
    06/4/2015 8 8
    07/2/2015 7 6
    08/3/2015 7 5
    09/10/2015 8 4

    Abbreviations: PSQI, Pittsburgh Sleep Quality Index; HAM-A, Hamilton Anxiety Rating Scale.

    Discussion

    The current case study found that CBD oil can be an effective compound to use for transitioning an individual off addictive use of marijuana. The fact that no changes were made in the patient’s medication schedule, diet, or lifestyle gives credence to the idea that the results were the actual effects of the CBD oil.

    A possible weakness of the study is the fact that the patient’s total nonuse of marijuana was self-reported, and the reliability of his reporting could be suspect. However, the patient made significant gains in taking responsible actions and presented fewer erratic and disorganized behaviors.

    A systematic review of the literature previously had examined 14 studies on the use of CBD oil to modulate various neuronal circuits involved in drug addiction.19 That review suggested that CBD “may have therapeutic properties on opioid, cocaine, and psychostimulant addictions … and may be beneficial in cannabis addiction in humans.” The current case study seems to support that review’s conclusions.

    One reported consequence of the cessation of daily marijuana use is a withdrawal syndrome that is characterized by irritability, anxiety, marijuana craving, decreased quality and quantity of sleep, and reduced food intake.16,20 The use of the CBD oil in transitioning the current patient off the marijuana allowed him to avoid experiencing those side effects, as was demonstrated by his behavior and scores on the PSQI and HAM-A screening tools.

    Patient Perspective

    The patient reported being less anxious and sleeping better since taking the CBD oil. He reported not using any marijuana since starting the CBD and was proud of his accomplishment of getting a job as a self-employed driver and continuing with teaching chess to children.

    Footnotes

    Author Disclosure Statement

    The author participated in no competing interests that would have affected the results of the case study. No financial support was provided by CannaVest at any time.

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