What is CBD Oil? The Many Treatment Options for Dogs with Epilepsy What Are the Benefits of CBD Oil for Dog Seizures? Is CBD Legal for Dogs? What Effects Does CBD Have on a Dog? Are There Any Negative Side Effects for Dogs? How Much CBD Should You Give a Dog with Seizures? How Can I Get a Hold of CBD Oil? Is CBD the Ri The best CBD oil for dog seizures contains the full spectrum of cannabinoids and terpenes, and offers higher dosages per serving. Here we highlight the most trustworthy brands. If your dog gets seizures, you’ll do anything you can to help him. Find out about the benefits of CBD oil for dogs with seizures …
CBD Oil For Treating Seizures & Epilepsy In Dogs
Dog seizures and epilepsy in general are scary for anyone to witness, but when it is your dog, it is emotionally wrecking to watch. It leaves you feeling helpless and distraught, which is the opposite of how we like to feel when it comes to our babies. We want them to know they are safe with us and that we will take care of them, no matter what.
Dogs seizures and epilepsy in dogs can be difficult to treat because there are many possible causes for them. CBD is a discovery that has proven to help with seizures in humans. It’s not a big jump to think that it could help pets as well. Many people have been using CBD oil as a natural therapy for dog seizures of all types with promising results.
What is CBD Oil?
Canine CBD oil is an extracted from hemp plants. It is one of over 100 cannabinoids found in cannabis plants (hemp is in the cannabis family). CBD is short for cannabidiol. Cannabidiol, or CBD, is equally as familiar to most people as tetrahydrocannabinol THC is.
Tetrahydrocannabinol THC is the psychoactive compound found in marijuana that is responsible for the head high experienced from using it. But CBD products derived from a hemp plant are free of toxins, psychoactive properties, and other high related side effects. Hemp is free from THC because the hemp plant itself contains less than 0.3% of THC in the first place.
With such a small amount of THC, hemp is considered free from it because this value is considered a trace amount. All canine CBD products are free of low quality ingredients and any related toxins.
Luckily, CBD doesn’t have that impact on the brain, but it still has many of the same medicinal uses as marijuana. Dogs, however, cannot have tetrahydrocannabinol. It’s toxic for them, so you should avoid THC products. High quality CBD, however, is safe for them. So far, there have been no documented ill-effects from the use of CBD for dogs, or humans for that matter.
The Many Treatment Options for Dogs with Epilepsy
Before we dive into the benefits of CBD oil for dog seizures, let’s explore medications used to treat dog seizures that aren’t CBD products. CBD oils are an all natural way of helping dogs with seizures and seizure control but there are many other treatment options for dog seizures, including:
- Potassium bromide
- Anticonvulsant drugs
- Treatment for pain relief
What Are the Benefits of CBD Oil for Dog Seizures?
So, if there are already many different treatment options for seizures in dogs, then why do people turn to CBD oil for dog seizures? Well, it all comes down to the way CBD oil offers numerous benefits, the first of which is the fact that CBD products don’t contain any unnatural ingredients. In other words, everything about CBD is natural.
CBD comes from a hemp plant, which is part of the cannabis plant family. However, hemp is not the same as the cannabis everyone assumes it is. While cannabis can get you high, a hemp plant is different because it doesn’t have enough THC to cause those psychotropic side effects. Instead, hemp can be used to treat pain from a head injury, offer relief from pain, and provide you with a way to manage your dog’s symptoms from seizures in dogs.
Plus, dog owners should know that a dogs body is already equipped with the internal processes that allow them to consume CBD oils for dog seizures. In your dog’s body, there are what’s known as CB1 receptors which are responsible for breaking down CBD molecules. They play a role in making CBD dog effective for seizures in dogs and helping dogs with seizures find relief from seizure discomfort.
CB1 receptors are a natural receptor in the body. But what is a receptor? Essentially, they are a main player in the overall functionality of the brain. They make it possible for compounds, molecules, and other elements that pass through the brain-blood barrier to be broken down effectively. There are numerous different kinds of receptors in the brain, and they all serve their own unique function.
Basically, these receptors are part of the endocannabinoid system, which is similar to the nervous system. However, the main difference is the purpose that these systems are designed for, with the endocannabinoid receptor being responsible for breaking down CBD and the nervous system existing for the purpose of regulating your dog’s homeostasis.
Is CBD Legal for Dogs?
One question that pops up all the time asks if cannabidiol is safe in the first place. Well, thanks to the signing of the Farm Bill of 2018, CBD has been legal, coast to coast, in the USA since January 1st, 2019. Before that, there had been an easing of regulations. However, before then, CBD still wasn’t legal worldwide. Did you know that one of the first places to legalize CBD is Colorado State? Many other US states followed suit.
Speaking of Colorado, many studies have been conducted regarding CBD for dogs at Colorado State University. Awhile back, researchers at Colorado State University, including Dr. Stephanie McGrath, started looking into the effects of CBD on canine seizures in dogs. Currently, researchers are continuing to conduct research in an attempt to better understand how CBD is absorbed by the bodies of cats and dogs.
We already know that the endocannabinoid system makes it possible for dogs and cats to consume, digest, and make use of cannabidiol CBD. Also known as the ECS receptors, the endocannabinoid system is like a nervous system for cannabidiol CBD. Just like the nervous system, the ECS is a natural system in our bodies that contains cb1 receptors and other related receptors.
Pet owners and their pets alike all have an endocannabinoid system. Within the ECS, there are endocannabinoid receptors which bind to CBD molecules found in CBD products. Without endocannabinoid receptors, a doga wouldn’t be able to break down CBD oils.
Researchers in Colorado are taking it a step further by looking at dogs seizures and how CBD is digested by a dog’s body. Through a clinical trial, researchers are able to look more closely at the effects of CBD on seizures in dogs and cats, too.
The new bill addressed the issue in a far more direct manner, making hemp products legal to manufacture and possess/use. The bill opened the door for CBD oil, produced from hemp, to be sold anywhere, in all 50 states within the US. Some places in the world still haven’t made CBD use legal, so it is best to check before you pack it for traveling out of the country. You should only use it and take it where it is legal or risk legal repercussions in those countries.
What Effects Does CBD Have on a Dog?
Dog owners should do their thorough research before giving dog CBD oil to their dogs with epilepsy. Even though a CBD product is considered safe, the health of your dog is a priority and you should always look into the quality of CBD oil for dogs with dog seizures before administering CBD oil to your dog.
In terms of the effects that CBD oil has on a dog, it has been shown in more than one CBD clinical trial that CBD oil has been used as a pain reliever and seizure reducing supplement when given to dogs with idiopathic epilepsy. Many owners report that it has lessened the severity and frequency of dog seizures. Many times, there is pain that follows seizures because of the intense cramping of muscles during seizures. CBD can also help manage this pain.
Are There Any Negative Side Effects for Dogs?
There are very few, and rare, side-effects from using CBD oil for dogs. The thing most reported is diarrhea. Issues with digestion only seem to happen if the dog or cat ingests too much right away. It takes time for them to adjust to the oil in its system. If diarrhea starts, lower the dose or even skip it for a day or two until it regulates. Then start the treatments again at a lower dosage.
Cannabidiol treats anxiety in many cases, which gives your pet a sense of control again. Anxiety can have physical symptoms that heighten the side effects of a seizure, so adding CBD as part of a dog’s seizure treatment plan can help alleviate anxiety stemming from every seizure, too!
How Much CBD Should You Give a Dog with Seizures?
Speaking of dosage, a dog with seizures will not need the same amount of CBD as every other dog with seizures. Rather, a dog with seizures will require a unique dose based on their body weight. Your dog’s CBD dosage will also depend on existing health problems beyond the seizure they experience frequently, but a seizure will also play a role in calculating the right dosage for your dog with seizures.
When preparing the administer cannabidiol to a dog experiencing seizures, it’s important to read the label on the bottle. Some labels will encourage you to administer a dog’s dosage twice a day, while others will recommend one daily dosage instead.
With seizures, a dog’s frequency may differ. It all comes down to how your dog’s brain responds to each frequency of CBD. For instance, some dogs with seizures may benefit from a higher frequency of two or three doses per day, whereas dogs with less severe seizures might just need one dose per day.
The health of your dog is all that matters, and it’s important to get their health under control, which CBD treats, oils, and supplements can help with! Dogs should be at least 12 weeks old before taking treats or other products. Since seizures stem from the brain, and CBD affects the brain, your dog’s vet will want to make sure your dog’s brain is developed enough before taking it.
How Can I Get a Hold of CBD Oil?
The first thing that you should do, especially if your pet is receiving treatment for any medical issues, is to speak to your veterinarian. Because you work with your veterinarian as a team for your pet’s health, you should both be on the same page. Find out what your vet thinks about using CBD oil and get his permission first.
You also will want to do some research. As fast as you learn about CBD dog, there is new information coming forth. The sheer speed at which research is coming out is mind-boggling. It’s essential to learn as much about it as you can, what is a suitable type of oil, what is the best CBD oil for dogs, and which delivery method you feel is best for your pet. There are treats, edibles, drops, and more that you can choose to give doses to your dog.
Is CBD the Right Option for My Dog?
It is possible. There’s no way to know for sure until you try it and use it long enough to get to the right dose. The research done so far shows that CBD can have a tremendous positive impact on seizure activity. Follow the recommendations, speak to your vet, and do your research. Learn as much as you can so that you can choose a high-quality oil. The more you learn, the better odds you’ll have at helping your dog with CBD.
Best CBD Oils for Dogs With Seizures & Epilepsy (2022)
Dogs can suffer from seizures due to a variety of reasons, from underlying health conditions to toxins.
CBD oil has been shown as one of the best natural remedies for dog seizures and related symptoms — making it a viable alternative to conventional prescription drugs.
In this article, we shed light on the best CBD oils for dog seizures, explain how CBD may help your canine friend, and how to ensure a well-informed purchase.
CBD & Dog Seizures (Highlights)
- Seizures are sudden changes in behavior caused by abnormal electrical activity in the brain. They can occur as trembling, twitching, confusion, drooling, loss of balance or consciousness, involuntary urination, and convulsions.
- Dogs may seize due to food poisoning, diseases like distemper, liver disease, kidney failure, brain injury, cancer, a stroke, or a hereditary disease such as epilepsy.
- Conventional medications may provide short-term relief from dog seizures, but they come with unpleasant side effects, such as headaches, irritation, hypersensitivity, nausea, vomiting, and sedation.
- CBD is one of the two major cannabinoids from cannabis plants. It’s non-intoxicating, so it won’t get your dog high. It can, however, help with the management of a wide range of symptoms and health conditions, including seizures.
- By interacting with the endocannabinoid system (ECS), CBD reaches specific receptors in the brain and dampens the activity of the nervous system – reducing the frequency and intensity of dog seizures.
- In one clinical trial, 89% of dogs that received CBD had a reduction in the frequency of seizures. The research team concluded the results were significant and promising for future research.
- Consult your veterinarian before giving your dog CBD oil for seizures. CBD interacts with at least 60% of prescribed medications, so a consultation with a vet will help you avoid the risk of cross-side effects resulting from those interactions.
Best CBD Oil for Dog Seizures
1. Royal CBD
Get 15% off all Royal CBD products. Use code “CFAH” at checkout.
- Non-GMO, pesticide-free hemp from Colorado
- CO2 extraction
- Full-spectrum CBD
- Up to 500 mg per bottle
- Bacon flavor
- Third-party tested for potency and purity
- Limited flavor options
- Not available in local stores (yet)
Royal CBD is a premium brand that uses the same premium-quality CBD extracts in its line for pets as it does in its collection for humans — ensuring the highest safety and efficacy.
These CBD pet oils are considered one of the best CBD oil for dogs which contain the full spectrum of cannabinoids and terpenes, leveraging the entourage effect in hemp and increasing CBD’s efficacy overall.
You can choose from two potencies: 250 mg (small and medium dogs) and 500 mg (large dogs).
The oil is suspended in organic MCT oil that boosts its absorption and ‘dilutes’ the hempy flavor.
Speaking of which, if your buddy dislikes the taste of unflavored CBD oil, the bacon-flavored version will change its mind in the nick of time.
All Royal CBD products are triple-tested in an ISO-certified laboratory, with complete results for the potency of CBD, the entire cannabinoid and terpene profile, and contaminants like pesticides, heavy metals, solvents, and mold.
2. Gold Bee
- Organic hemp
- Supercritical CO2 extraction
- Full-spectrum CBD
- 600 mg per bottle
- Batch-specific lab reports
- Only one strength is available
- It can be difficult to dose in smaller dogs
Gold Bee is a company founded by people with remarkable expertise in the superfoods industry. Its products are made in one facility and in small batches, ensuring top-shelf quality.
Gold Bee offers all-organic products for dogs, such as full-spectrum CBD oil and CBD Goofy Bones (treats). Look for these products in CBD stores for dogs near you.
The oil contains 600 mg of full-spectrum CBD, sourced from organic, terpene-rich hemp strains that Gold Bee grows in collaboration with local farmers. It comes in a delish peanut butter flavor.
At 20 mg of CBD per mL, this oil is a great pick for larger dogs and those whose seizures require high doses of CBD daily. You can also give it to a medium-sized dog and benefit from longer-lasting supplies.
However, when it comes to small breeds like Schnauzers or Chihuahuas, we recommend the low-potency option from Royal CBD.
Does CBD Oil Help Dogs With Seizures?
Yes, a few studies — including one clinical trial — as well as anecdotal evidence from dog parents indicate that CBD can help with dog seizures.
CBD targets specific receptors in the brain (TRPV1 and GPR55) to prevent excessive activity in the central nervous system.
It also helps raise GABA levels — another inhibitory neurotransmitter.
The above mechanisms answer why CBD appears to help where conventional seizure medications fail to produce the desired results.
In fact, CBD became popular worldwide because of a young girl Charlotte Figi whose parents used CBD to reduce the frequency and severity of human epileptic seizures with great success.
CBD stands out from other health supplements thanks to its versatility. Not only can it help with dog seizures, but it also aids in reducing anxiety, joint pain, digestive problems, inflammation, and loss of appetite.
Here we explain what makes CBD so special.
How CBD Works to Reduce Seizures in Dogs
The anti-epileptic mechanism of CBD in dogs stems from its interaction with the endocannabinoid system (ECS).
The ECS is a complex neurochemical network made of neurotransmitters (endocannabinoids), receptors, and enzymes. Together, these components create the master regulatory system in all mammals that promotes and helps maintain homeostasis throughout the body.
CBD and Cannabinoid Receptors
CBD indirectly acts on the activity of CB1 receptors in the brain. It also binds to CB2 receptors, whose highest concentrations can be found in the immune system and peripheral organs.
Seizures are bursts of uncontrolled activity between the nerve cells. It leads to disrupting the distribution of signals and inflicts inflammation upon neurons.
Studies have found that ECS and epilepsy are closely linked together. CBD has been highlighted by researchers as a potential anticonvulsant, anti-inflammatory, and neuroprotectant.
Hence its potential to treat epilepsy in dogs.
Is CBD the Only Anti-epileptic Cannabinoid?
CBD oil contains more than 400 chemical compounds. Another anti-epileptic cannabinoid is CBDV (cannabidivarin). Both cannabinoids interact with the TRPV1 receptor.
This receptor mostly occurs in the brain’s hippocampus region. It controls many cognitive processes, such as memory, learning, and decision making — but it’s also associated with seizure activities.
One theory proposes that CBD and CBDV can prevent epilepsy by blocking the overexcitement of this receptor.
In a similar fashion, CBD can modulate the activity of neurons by acting on other seizure-related receptors, such as G-protein-coupled receptor-55 (GPR55) and the equilibrative nucleoside transporter 1 (ENT-1).
Studies on CBD and Dog Seizures
- A 2019 study published in the journal Molecules concluded that CBD is a potentially effective remedy for epilepsy, and it comes without the side effects of conventional anti-epileptics.
- A 2017 study compared the anticonvulsant effects of CBD and CBD. The authors concluded that CBD has a stronger anticonvulsant profile than THC.
- In another 2021 study, the researchers found that CBD enhanced the efficacy of clobazam, a common pharmaceutical anticonvulsant.
What Are Clinical Trials Saying About the Efficacy of CBD Oil for Dog Seizures?
CBD shows significant potential as a treatment for dogs with seizures. The AKC Canine Health Foundation (AKC HF) has recently run a clinical trial that analyzed the efficacy of CBD oil for dogs with epilepsy.
This was the first study that used whole-plant CBD oil instead of synthetic cannabidiol.
The experiment was conducted by two important scientists in the veterinary space – Stephanie McGrath, a veterinary neurologist at Colorado State University, and Diane Brown, the CEO of the AKCC HF.
The study started by administering CBD oil to nine dogs and a placebo to seven others in laboratory conditions. Neither the owners nor the scientists knew which substances each dog took.
The team monitored the dogs with seizures for the next three months. Once the trial ended, the dogs went through a 4-week washout period. At the end of the study, each dog received whichever substance they didn’t get the first time for the same time.
As reported by Science Daily, 89% of dogs in this study experienced a significant reduction in the severity and frequency of seizures. The result was statistically significant, showing great promise for parents who want to use CBD oil to treat epilepsy in their four-legged friend.
How to Give Dogs CBD Oil for Seizures
Consistency is critical if you want to achieve the best results with CBD and significantly reduce seizures in your dog.
You need to administer it regularly.
Not just during a seizure attack but every single day.
CBD modulates and helps optimize your dog’s ECS, so if the seizures stem from a clinical endocannabinoid deficiency, you can use CBD and other cannabinoids in CBD oil to regulate the activity of brain cells.
This makes CBD a potential preventive option when it comes to dog seizures.
How Long Does It Take for CBD to Work for Dog Seizures?
The acute effects of CBD oil on the nervous system can take anywhere from a few minutes to half an hour to take hold. However, for effective seizure management, you may need to show more patience — for up to two weeks.
If you do not see any results, increase the dosage and continue for around 5 days. Repeat until you find the optimal amount of CBD for your dog.
CBD and Dog Seizure Medication: Can You Give Them Together?
Earlier, we mentioned that CBD could potentiate the effects of clobazam, an anticonvulsant drug used to treat epilepsy.
That’s because CBD interacts with a broad range of pharmaceutical medications.
CBD is a potent inhibitor of the CYP450 enzyme system — a set of enzymes that metabolize the majority of drugs in the liver. When it interacts with a drug, it can increase or decrease its levels in the bloodstream.
When you use high doses of both substances together, CBD could potentially lead to a dangerous buildup of the drug — and cause toxicity.
Sometimes, CBD may hinder the efficacy of drugs; it depends on the type of interaction in the liver.
Talk to your doctor before giving your dog CBD oil for seizures; it’s the best choice to avoid the said interactions and ensure safe supplementation.
How Much CBD Oil Should I Give My Dog for Seizures?
You’ll need to experiment most of the time.
Every dog is different, and since CBD isn’t regulated by the FDA, there is no official serving size or dosage chart for CBD for dogs when it comes to general supplementation — let alone medical conditions.
As a rule of thumb, you should follow the manufacturer’s instructions on the packaging. Start at the low end, e.g., with ¼ – ½ dropper, and see how your dog responds to that dose.
Experts recommend giving 0.25 – 0.5 mg of CBD for every pound of the dog’s weight. Obviously, a 30-pound dog will need less CBD than a 60-pound breed.
As you start adding CBD oil to the dog’s routine, slowly adjust the dosage until you find the amount that works best for its seizures, and avoid having your dog overdose with CBD oil.
Looking for more answers about seizures and how CBD oil can help? Here are the most frequently asked questions.
What are seizures?
The term ‘seizure’ refers to a sudden change in behavior caused by unusual electrical activity in the brain. They often manifest as trembling, drooling, twitching, loss of balance, convulsions, and loss of consciousness.
Although some seizures might be mild, others can last for minutes and cause issues with coordination or other health concerns for hours after the attack is over.
Most of the time, seizures indicate serious health problems such as epilepsy, organ failure, rabies, brain tumors, or liver disease.
Why do dogs seize?
10 million dogs in the United States have seizures. The causes and severity vary; a dog may seize because of diseases like liver disease, epilepsy, or kidney failure, but it may also occur as a result of food poisoning or an injury to the brain or spine.
How will I know if my dog is having seizures?
If your dog is having a seizure, it will give telltale signs, such as head or eye twitching, whimpering, whining, rapid body movements, growling, or loss of consciousness.
Seizures can be as short as a few seconds up to several minutes and may also cause involuntary urination or defecation.
What should I do when my dog has a seizure attack?
First of all, notice how long it lasts and observe any changes to your dog’s behavior once the seizure is over. If your dog doesn’t regain consciousness, take them to the vet or the nearest emergency room right away.
Other animals and people should be kept away from your seizing dog. Stay with your buddy until the seizure ends, and refrain from placing any objects or your hands in their mouth, as they may accidentally snap it. When your dog is choking, the Heimlich maneuver may come in handy.
Dogs are more likely to have another seizure after a day or two from the first one, so make sure to keep a close eye on your dog for the next 24 hours. While most dogs recover from seizures without help, some may suffer from severe side effects and require medical intervention.
Epileptic dogs usually experience more seizures than dogs with other conditions, so it’s important to monitor your dog’s behavior to notice any changes that could indicate another seizure.
What are some other medications for dogs with seizures?
- Antidepressants: amitriptyline is one of the commonly prescribed antidepressants for dog seizures because it can reduce the severity and frequency of seizures in some dogs.
- Benzodiazepines: drugs such as diazepam and midazolam can be used to relieve anxiety and panic during a seizure.
- Phenobarbital: this is a barbiturate that doctors use to manage seizures in dogs.
- Potassium bromide: also used to manage seizures, potassium bromide can be used on its own or in conjunction with phenobarbital.
- Zonisamide: Another anticonvulsant that doctors sometimes prescribe to dogs with seizures.
Do vets recommend CBD oil for dogs with seizures?
Although CBD oil isn’t a prescription drug and veterinarians can’t officially prescribe it, many vets now recommend CBD oil for dog seizures because the benefits outweigh the risk. Veterinarians often choose CBD oils as the go-to format, but in some cases, treats or a topical product may be recommended.
Can CBD oil make seizures worse?
CBD oil shouldn’t make seizures any worse. In fact, it can reduce the frequency and severity of seizures in some dogs. However, if you give your dog another medication in combination with CBD oil, such as phenobarbital or clonazepam, you should consult with a veterinarian.
If your dog receives two similarly acting compounds, it can lead to overdose symptoms, such as sedation, drowsiness, and confusion.
Can I give my dog CBD every day?
Yes, CBD is non-intoxicating, so it won’t get your dog high. It’s also non-toxic, meaning you can safely use it as a daily health supplement.
However, make sure that your CBD oil comes from organic hemp and has been extracted with CO2 to ensure maximum purity.
Speaking of which, you can easily verify the product’s purity by looking at its certificate of analysis (CoA) from a third-party laboratory.
Never trust a CBD brand that doesn’t post the lab reports on its website or, at least, send it to customers via email.
Is CBD safe for dogs?
Yes. CBD oil is a natural product with a remarkable safety profile. Even the World Health Organization (WHO) acknowledges CBD as safe and well-tolerated by humans and animals.
Key Takeaways on the Best CBD Oils for Dog Seizures
More and more dog parents are turning to CBD oil in hopes of relieving seizures in their furballs.
Unlike conventional seizure medications, CBD has a decent safety profile and uses certain neurochemical mechanisms that these drugs ignore.
Not only can CBD reduce the intensity of a seizure, but it can also prevent it by modulating the communication between neurons in your dog’s brain — bringing them to the state of homeostasis.
Always choose third-party lab-tested products that come from organic hemp, such as the brands we’ve mentioned in this article.
Check up with your veterinarian before giving your dog CBD oil for seizures; doing so will help you prevent negative interactions with other medications and gauge the most effective dosage.
- Zou, S., & Kumar, U. (2018). Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. International journal of molecular sciences, 19(3), 833. https://doi.org/10.3390/ijms19030833
- Iannotti, F. A., Hill, C. L., Leo, A., Alhusaini, A., Soubrane, C., Mazzarella, E., Russo, E., Whalley, B. J., Di Marzo, V., & Stephens, G. J. (2014). Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability. ACS chemical neuroscience, 5(11), 1131–1141. https://doi.org/10.1021/cn5000524 
- Sharir, H., & Abood, M. E. (2010). Pharmacological characterization of GPR55, a putative cannabinoid receptor. Pharmacology & therapeutics, 126(3), 301–313. https://doi.org/10.1016/j.pharmthera.2010.02.004 
- Silvestro, S., Mammana, S., Cavalli, E., Bramanti, P., & Mazzon, E. (2019). Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials. Molecules (Basel, Switzerland), 24(8), 1459. https://doi.org/10.3390/molecules24081459 
- Perucca E. (2017). Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?. Journal of epilepsy research, 7(2), 61–76. https://doi.org/10.14581/jer.17012 
- Chuang, S. H., Westenbroek, R. E., Stella, N., & Catterall, W. A. (2021). Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome. Journal of experimental neurology, 2(2), 81–85. https://doi.org/10.33696/neurol.2.040 
- McGrath, S., Bartner, L. R., Rao, S., Packer, R. A., & Gustafson, D. L. (2019). Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional anti-epileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy. Journal of the American Veterinary Medical Association, 254(11), 1301–1308. https://doi.org/10.2460/javma.254.11.1301
Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.
Benefits Of CBD Oil For Dogs With Seizures
If your dog suffers from seizures, you’ve felt the stress and helplessness. So if you’ve been researching and wondering if CBD oil for dogs with seizures is a good option … I’m glad you found this post!
It’s hard to see your dog suffer and not be able to explain to him what’s happening and why.
If you’ve visited your vet already and haven’t found any answers you’re not alone. Or maybe you’re looking for an alternative to the medication the vet prescribed?
Regardless of what brought you here today, if your dog is prone to seizures, you want a way to help … and CBD oil for dogs may be just the answer you’re looking for.
And yes, it’s legal!
Seizures In Dogs
Seizures in dogs can manifest as anything from a twitch to uncontrollable shaking. They might be over quickly, or they can last for several minutes. Causes of seizures vary from dog to dog.
There are several different things that cause seizures:
- Underlying health condition like liver or kidney disease or cancer
- Electrolyte problems
- Topical flea and tick products
- Herbicides and pesticides
- Head injury
CBD Oil For Dogs With Epilepsy
If your dog suffers from regular seizures, epilepsy might be the culprit. Epilepsy means there are bursts of uncontrolled electricity in your dog’s brain. Sometimes there’s no cure for this condition, but you can manage it naturally with CBD oil.
CBD stands for Cannabidiol. It’s harvested from the cannabis hemp plant. However, unlike tetrahydrocannabinol (THC), CBD has no psychoactive properties .. so it won’t make your dog high.
This is because of the way CBD is structured. That structure affects CBD’s impact on the brain, nervous system and throughout the body.
The psychoactive effect of THC comes from the way it binds with receptors in the brain, called endocannabinoids. CBD also interacts with these endocannabinoid receptors.
Endocannabinoids are found throughout the body. The highest concentration is in the brain, spinal column, and nervous system. And it’s in these organs and systems that CBD has the greatest potential to help dogs with seizures.
CBD Oil For Seizures In Dogs
Scientists are discovering a wide variety of uses in both humans and dogs. And one of the most important uses of CBD oil for dogs is in the management of seizures. Studies as well as anecdotal evidence have shown CBD to be highly effective at managing seizures. But you don’t want to give your dog something without knowing exactly what it is and what it’s going to do.
So … how does CBD oil work?
Earlier I mentioned those endocannabinoid receptors. And they’re important when it comes to CBD oil for seizures in dogs.
There are two types of endocannabinoid receptors in your dog’s body.
- The CB2 receptors – mainly in the immune system.
- The CB1 receptors – centralized in the nervous system and the brain.
It’s these CB1 receptors that have the greatest impact on your dog’s seizure treatment. Studies suggest that the endocannabinoid system is altered by seizures and epilepsy.
Research shows that CBD improves seizure control in patients with specific epilepsy syndromes. Seizures can have profound effects on the endocannabinoid system. This is why CBD, through a process known as “external modulation,” can reduce and sometimes stop seizures from happening.
The exact way CBD contributes to a reduction in seizures and affects the Endocannabinoids system (ECS) is still unknown. One theory is that CBD affects the receptors that calm the neurons that fire during a seizure. But there’s still further investigation needed to learn more.
But we do know that CBD oil can have a positive effect on your dog’s seizure activity. If he feels any side effects at all, it will most probably take the form of mild drowsiness.
**Note. Even big pharma has finally recognized the power of CBD oil for seizures. And in June 2018, the FDA approved the first drug containing CBD for the treatment of epilepsy.
CBD Dose For Dogs With Seizures
CBD oil dosage for your dog depends on his size. Smaller dogs require lower dosages, of course, and larger dogs will need more to see an effect. You can make these determinations based on your dog’s weight. It’s best to follow the label directions on the product you buy.
Look for CBD oil with the following features:
- Full spectrum or broad spectrum
- Preferably organic
- Extracted using C02 extraction, without solvents or chemicals
- Manufacturer provides Certificate Of Analysis from a third party lab, showing that the product is what’s claimed on the label, and is free of contaminants, additives or preservatives
Full spectrum CBD oils in tincture form usually work best. If your dog is hard to dose, chewable tablets or treats may be easier. But be aware these products may not contain sufficient levels of CBD to help with seizures.
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CBD oil for seizures in dogs is a natural alternative with minimal side effects and a very promising future.
Carlini EA, Cunha JM. Hypnotic and antiepileptic effects of cannabidiol. J Clin Pharmacol. 1981 Aug-Sep;21(S1):417S-427S.
Kogan L et al. US Veterinarians’ Knowledge, Experience, and Perception Regarding the Use of Cannabidiol for Canine Medical Conditions. Front Vet Sci. 2019 Jan 10;5:338.
McGrath S et al. Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy. J Am Vet Med Assoc. 2019 Jun 1;254(11):1301-1308.
Rosenberg EC, et al. Cannabinoids and Epilepsy. Neurotherapeutics. 2015;12(4):747-768.
Perucca E. Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last? J Epilepsy Res. 2017;7(2):61-76. Published 2017 Dec 31.